Infantile functional dyspepsia syndrome is a common syndrome complex of digestive system in children aged 0 to 3 years. Clinically, it is mainly characterized by such symptoms as decreased appetite, belching and abdominal distension, retching or vomiting, repeated crying, abdominal pain, and abnormal defecation, which seriously affect the growth, development and quality of life of infants. Both traditional Chinese medicine (TCM) and western medicine have certain advantages in the treatment and management of this disease. Led by the National Clinical Collaboration Group for Integrated Traditional Chinese and Western Medicine on Pediatric Functional Dyspepsia—a major difficult disease program, the consensus was developed through cooperation with integrated TCM and western medicine experts in pediatric gastroenterology, experts in pediatric Tuina and external therapy, and experts in methodology. Based on the concept of integrating TCM and western medicine, this consensus clarifies the diagnostic criteria and key points of TCM syndrome differentiation, and establishes a comprehensive intervention system centered on protecting and reinforcing the spleen and stomach. Western medicine focuses on nutritional management and feeding guidance, recommending appropriate formula milk and scientific complementary feeding. TCM interventions mainly include pediatric Tuina, acupoint application, and dietary therapy, combined with personalized care guidance. This consensus provides a basis for standardized clinical diagnosis, treatment and family care, which is of great significance in increasing the level of integrated TCM and western medicine in the management of this disease.