ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

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    Experience in the diagnosis and treatment of children's diseases from "accumulated internal heat"
    ZHANG Yu, XIAO Yang, ZHOU Mengxiao, SUN Liping
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 59-63.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.012
    Abstract (2941)      PDF(pc) (1073KB)(6642)       Save
    The function of the spleen in children is often insufficient, and improper feeding, or disease damage may cause the fact that food can't be digested, which is food accumulation。Although it is a disease of the spleen, Professor Sun Liping believes that long time of food accumulation can form internal heat syndrome, thereby inducing a variety of pediatric diseases. Attention should be paid to the physical changes caused by congenital abnormality and acquired dystrophy. Based on the physiological and pathological characteristics of children, Yin and Yang theory, five-element theory and constitution theory, and through combination with more than 30 years of clinical experience of Professor Sun Liping, this paper explores the etiology and pathogenesis of children's diseases caused by "food", the disease outcome transformed by "heat", the diagnosis experience from "observation", and the treatment method by "elimination". A new line of thinking of "same treatment for different diseases" is provided for the diagnosis and treatment of abdominal pain, cough, asthma and tic disorders caused by food accumulation.
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    Meta analysis of the efficacy and safety of traditional Chinese patent medicine in the treatment of tic disorders in children
    LI Ruiben, NIE Lianghui, YANG Libin, MA Rong
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (6): 479-485.   DOI: 10.3969/j.issn.1674-3865.2023.06.004
    Abstract (1462)      PDF(pc) (3684KB)(5697)       Save
    Objective To systematically evaluate the efficacy and safety of traditional Chinese patent medicine in the treatment of tic disorders in children.Methods Randomized controlled trials of traditional Chinese patent medicine in the treatment of tic disorders in children were comprehensively searched in CNKI,Wanfang Database,VIP,China Biomedical Database,Pubmed,Embase and Cochrane Library.Two independent researchers screened and evaluated the quality of the literature based on pre-set inclusion and exclusion criteria,and made a meta-analysis of the included literature using RevMan 5.3 software.Results A total of 3 088 pediatric patients were ultimately included in 12 studies.Meta analysis showed that the effective rate of traditional Chinese patent medicine was higher than that of the placebo group,with a statistically significant difference [RR=2.06 (1.63,2.62),P<0.000 01].The effective rate of traditional Chinese patent medicine was not significantly different from that of tiapride hydrochloride [RR=1.03 (0.98,1.07),P=0.23].In terms of tic severity,traditional Chinese patent medicine could significantly reduce the total score of YGTSS compared with placebo [MD=-7.84 (-10.18,-5.51),P<0.000 01].Comparing traditional Chinese patent medicine with tiapride hydrochloride,there was no statistically significant difference in the reduction of the total score of YGTSS [MD=-0.32 (-1.21,0.58),P=0.75].In terms of adverse events,the incidence of dizziness,fatigue and sleepiness of traditional Chinese patent medicine was lower than that of tiapride hydrochloride.Conclusion Traditional Chinese patent medicine is effective and safe in the treatment of tic disorders in children,which still needs to be confirmed by more high-quality randomized controlled studies.
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    Individualized intervention strategies in the treatment of childhood and adolescent obesity based on precision medicine
    LI Ping, YANG Fan, LIU Hanmin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 1-7.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.001
    Abstract (3654)      PDF(pc) (1165KB)(4874)       Save
    Childhood and adolescent obesity has become a global challenge in public health.Its high weight regain rate and risks of metabolic complications highlight the limitations of traditional intervention strategies.This review systematically explores individualized intervention strategies for obesity in children and adolescents in the context of precision medicine,breaking the traditional "one-size-fits-all" model.It integrates multi-omics technologies with intelligent management methods,proposing a multidimensional framework for precise intervention.First,a precise diagnosis and evaluation system is constructed based on multi-modal data,including genomics,radiomics,and gut microbiomics,to identify genetic susceptibility,metabolic phenotypes and microbiome characteristics,laying the foundation for stratified interventions.Secondly,individualized intervention plans are developed based on genetic risk scores,epigenetic regulatory mechanisms,and gut microbiome-targeted therapies:gene-guided strategies aim to optimize dietary structure through multi-gene risk assessments; epigenetic interventions aim to regulate DNA methylation and histone modification by taking advantage of nutrients (such as methyl donors and short-chain fatty acids),reversing metabolic dysregulation; microbiome remodeling aims to improve energy metabolism balance through probiotics and synbiotics.Furthermore,artificial intelligence and wearable devices are employed for dynamic monitoring in multiple scenarios.By collaborating with multidisciplinary teams in nutrition,sports medicine,and psychology,a smart management model of "hospital-family-community" network is established.While precision medicine offers groundbreaking directions for childhood obesity treatment,challenges such as biomarker validation,data integration,and long-term efficacy evaluation remain to be addressed.This review provides theoretical foundations and practical pathways for the improvement in the effectiveness and sustainability of interventions,emphasizing the need to integrate interdisciplinary innovative technologies in the future in order to promote the transformation of childhood obesity management toward precision and intelligence.
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    Analysis of direct medical cost in children with acute lymphocytic leukemia
    YAN Yuzhu, YU Jie, AN Xizhou, GUO Xiaoli, YAO Juan, DENG Zhifen, ZHANG Wenjun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (2): 136-139.   DOI: 10.3969/j.issn.1674-3865.2024.02.008
    Abstract (2489)      PDF(pc) (974KB)(4058)       Save
    Objective To analyze the direct medical cost and composition ratio of children with acute lymphocytic leukemia,in order to provide basis for the reform of medical system and guarantee the standard treatment of children with leukemia.Methods A total of 110 children with acute lymphocytic leukemia were included in the study,who were treated in the Department of Hematology Oncology of Children′s Hospital Affiliated to Chongqing Medical University from Jan.2015 to Apr.2018.Descriptive analysis was used to analyze the direct medical costs of these children and investigate the main compositions.Results During the standard treatment of children with acute lymphocytic leukemia,the direct medical costs were mainly composed of outpatient costs (averaged 23 597 CNY),one-day chemotherapy costs (averaged 23 216 CNY),hospitalization costs (averaged 158 152 CNY).In the total cost of children with ALL,drug costs,treatment costs and laboratory test costs accounted for a large proportion.The average reimbursement rate was 59.1%(93 415/158 152).The average hospitalization time of children with acute lymphoblastic leukemia was 131 days,and the average daily hospitalization cost was 1 207 CNY(158 152/131).Conclusion Reducing drug costs and standardized treatment and testing can reduce medical costs.Comprehensive and multi-angle support should be provided for the families of children with leukemia,in order to guarantee the treatment for these children.
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    Case examples of Dong Youqi's application of Erchen decoction and its derivatives prescriptions in treating infantile phlegm-damp syndrome
    Wanying CHANG, Youqi DONG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (1): 67-70.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.01.013
    Abstract (1542)   HTML (3)    PDF(pc) (516KB)(3595)       Save

    Erchen decoction is the fundamental prescription for treating phlegm-damp syndrome and has been praised as "the general prescription for resolving phlegm" by physicians in the past dynasties. Children are constitutionally frail and prone to dampness retention and phlegm production due to dysfunction of the spleen in transportation; internal obstruction by phlegm-dampness can lead to multiple system disorders involving the respiratory, digestive and emotional systems. Considering the physiological characteristics of children such as "inherent splenic insufficiency" and "inherent pulmonary insufficiency", and based on the pathogenic theory that "the spleen is the source of phlegm production and the lung is the container for phlegm storage", Professor Dong Youqi adheres to the therapeutic principle of "regulating qi first for phlegm treatment and invigorating the spleen to cut off the source of phlegm". He flexibly applies Erchen decoction and its derivative prescriptions including Wendan decoction and Liujunzi decoction, with modifications tailored to syndromes, addressing both the symptoms and the root causes of the disease. These prescriptions have been widely used in the treatment of phlegm-dampness-related pediatric disorders such as cough, food stagnation, anorexia, vertigo, insomnia and emotional disorders, achieving remarkable therapeutic effects. This paper cites three typical medical cases as evidence, reflecting Professor Dong's academic thought of "diagnosing diseases and formulating treatments based on theoretical inference", and providing valuable clinical experience for the application of Erchen decoction and its derivative prescriptions in the treatment of infantile phlegm-damp syndrome.

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    A network Meta-analysis of the clinical efficacy of guideline-recommended external treatment of traditional Chinese medicine for anorexia in children
    Zhonghe ZENG, Longming LEI, Jun ZHAO, Qiongxiao WANG, Lin FU, Mengyun WU, Danlu SU, Guanghui CHEN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (1): 23-30.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.01.005
    Abstract (1893)   HTML (8)    PDF(pc) (1069KB)(3435)       Save

    Objective To evaluate the efficacy and safety of guideline-recommended non-pharmacological TCM therapies for pediatric anorexia via a network Meta-analysis. Methods RCTs from CNKI, Wanfang, PubMed, Web of Science, Embase, and Cochrane Library up to March 2025 were searched. Quality assessment used ROB 2.0,and data were analyzed with Stata 18.0. Results Thirty-eight RCTs (3 546 patients) covering pricking at Sifeng points, acupoint application, pediatric Tuina, and their combinations were included. Pricking at Sifeng points+pediatric Tuina was most likely the best intervention for overall clinical effectiveness(SUCRA=78.9%) and serum zinc improvement(SUCRA=95.1%).Pediatric Tuina+oral medication ranked highest for improving serum iron(SUCRA=85.7%) and serum calcium(SUCRA=83.4%). Conclusion Pricking at Sifeng points plus pediatric Tuina is recommended for overall efficacy and serum zinc, while pediatric Tuina with oral medication performs better for serum iron and calcium. Therapy selection should be individualized based on serological indicators. Further high-quality RCTs are warranted.

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    Treatment for pediatric pulmonary diseases based on the theory of "lungs governing skin and hair" and the method of "analogy and classification" 
    WEI Jiaxuan, YANG Jianhui, FENG Zhongfa, LI Rong, ZHAO Shun, LIU Qiaoya
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 75-78.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.016
    Abstract (2887)      PDF(pc) (1062KB)(3305)       Save
    This paper explores the application value of Traditional Chinese Medicine (TCM) theory of "lungs governing skin and hair" and the thinking method of "analogy and classification" in the treatment of pediatric pulmonary diseases.Both "lungs governing skin and hair" and "analogy and classification" are traditional TCM theoretical approaches guiding clinical differential diagnosis and treatment.By discussing the correlation between the lungs and the skin and hair,and then employing the method of analogy and classification,this paper explores the feasibility and efficacy of treating pulmonary diseases by the "skin"-cortex (the character of skin and cortex is the same in Chinese).Starting from the physiological characteristics of children,such as "lung deficiency" and loose cutaneous layers,the paper argues that "cortex-related" herbal medicines (e.g.,Baixian Pi,Hou Po,and Chan Tui) can improve the pathological features of being easily invaded by external pathogens in children.Through case studies,this paper demonstrates a formula containing cortex-related herbs in the treatment of cough (wind-phlegm obstructing the lung) in a 4-year-old child,which is very effective.The results confirm the clinical feasibility of this approach.By integrating traditional TCM theories with modern scientific validation,this paper provides new insights into the diagnosis and treatment of pediatric pulmonary diseases,highlighting the unique advantages of TCM in the field of pediatrics.
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    Exploring the pathogenesis of pediatric functional dyspepsia based on the theory of "spleen deficiency as the root"
    WANG Na, LIU Shiyu, LIU Jie, YU Jian, XIONG Lei
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (6): 477-481.   DOI: 10.3969/j.issn.1674-3865.2024.06.004
    Abstract (1977)      PDF(pc) (1035KB)(3257)       Save
    Functional dyspepsia(FD) is a common chronic gastrointestinal disorder in children,characterized by symptoms such as upper abdominal discomfort,abdominal distension,poor appetite,and acid regurgitation.The pathogenesis of FD is complex,involving multiple factors such as gastrointestinal motility disorders,visceral hypersensitivity,and brain-gut axis dysfunction.In traditional Chinese medicine (TCM),it is believed that the theory of "spleen deficiency as the root" is the core pathological mechanism.Specifically,spleen deficiency impairs the normal flow of qi,leading to the accumulation of dampness and stagnation,which brings about gastrointestinal motility issues and visceral hypersensitivity.Furthermore,spleen dysfunction weakens qi and hinders digestive absorption and blood production,worsening gut microbiota imbalances and disrupting brain-gut axis regulation.The TCM treatment strategy for FD involves four key approaches:strengthening the spleen,regulating spleen qi,activating spleen function,and balancing qi flow.Strengthening the spleen and eliminating dampness enhances gastrointestinal motility and removes stagnation.Regulating spleen qi improves digestion and relieves food retention.Activating spleen function restores healthy digestion and absorption.Balancing qi flow ensures smooth coordination of qi ascending and descending to relieve stagnation.These TCM methods align closely with modern medical strategies of regulating gastrointestinal motility,reducing visceral hypersensitivity,and balancing brain-gut axis.This study systematically explores the pathogenesis of FD and the treatment strategy of integrating TCM with modern medicine from the perspective of "spleen deficiency as the root".It highlights the intricate interactions among spleen function,the brain-gut axis,and gut microbiota.This research provides theoretical foundation and guidance for the treatment of children with FD.
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    Analysis of the clinical characteristics of leukemoid reaction in children
    SONG Yulei, LUO Haiyan, FAN Jianghua, YANG Longgui, XIAO Zhenghui
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (6): 531-535.   DOI: 10.3969/j.issn.1674-3865.2023.06.015
    Abstract (757)      PDF(pc) (815KB)(3035)       Save
    Objective To explore the clinical features of leukemoid reaction (LR) in children and the key points of differentiation from leukemia.Methods The clinical data of 89 children with leukocyte ≥30×109/L admitted to the internal medicine ward of Hunan Children's Hospital in the past two years (LR group) were retrospectively analyzed,including 44 cases of leukemoid reaction and 45 cases of leukemia.Another 89 children with non-leukemoid reaction(leukocyte <30×109/L) admitted in the same period were selected as the control group(NLR group).The general data,laboratory examination,hospital stay,discharge diagnosis and other clinical data of LR group and control group were statistically analyzed.The difference in laboratory indexes between LR group and leukemia group was compared.Results Compared with the non-leukemoid reaction(NLR) group,the ≥30×109/L group had a higher proportion of fever patients,longer hospital stay,higher neutrophil ratio and higher positive rate of blood culture.Pneumonia was the main diagnosis in the LR group,and the incidence of lung consolidation was statistically different between the two groups(P<0.05).The LR group in bacteremia patients had a higher gram-positive infection rate.The proportion of patients with leukocyte count ≥50×109/L in leukemia group was significantly higher than that in LR group,and there were statistically significant differences in platelet count,C-reactive protein,uric acid and lactate dehydrogenase levels between leukemia group and LR group.Conclusion Children with LR usually have a clear etiology and are at high risk for pneumonia and lung consolidation.A combination of clinical features and laboratory indicators can help early identification of leukemia in patients with leukocytosis.
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    Exploring the rehabilitation,diagnosis and treatment of autism spectrum disorder in traditional Chinese medicine based on Professor Xu Rongqian′s "Theory of Shen,Hun,Yi,Po,Zhi"

    ZHU Ling, YU Minfeng, LIU Zhenhuan, LI Nuo, LIU Ying, LI Longhua, HUANG Yinying, LIN Xiaohong, CHEN Kanghua
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (4): 333-338.   DOI: 10.3969/j.issn.1674-3865.2024.04.013
    Abstract (1159)      PDF(pc) (1117KB)(2975)       Save
    The occurrence of autism spectrum disorder (ASD) involves multiple organ dysfunction.Professor Xu Rongqian′s "Theory of Shen,Hun,Yi,Po,Zhi" can explain various core clinical manifestations of ASD.Through in-depth analysis of the functions of Shen,Hun,Yi,Po,Zhi,it has been discovered that the occurrence of this disease is closely related to the "Five Organs Shen",especially to the heart-Shen,liver-Hun,spleen-Yi,and kidney-Zhi.The theoretical system of "treatment for both Xing and Shen" is used in clinical practice to guide the treatment of ASD,which achieves good therapeutic effects by benefiting Xing and qi.
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    Data mining of medication rules of Professor Chang Ke in the treatment of cough in children
    Yali CUI, Ke CHANG
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (3): 264-269.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.03.015
    Abstract (1956)   HTML (4)    PDF(pc) (888KB)(2809)       Save

    Objective To analyze the medication rules of Professor Chang Ke in the treatment of cough in children,and summarize his thoughts on the treatment for cough. Methods Collect the prescriptions of Professor Chang Ke for the treatment of cough in the outpatient department from November 1,2023 to November 1,2024,standardize the drug names in the prescriptions,establish a database on the ancient and modern medical record cloud platform,and use multiple analysis methods to analyze the collected data from multiple perspectives,in order to explore the medication rules of Professor Chang Ke in the treatment of cough. Results A total of 567 prescriptions involving 224 Chinese medicines were included. According to the analysis of the data from the cloud platform of ancient and modern medical records, it was concluded that the high?frequency drugs were Scutellaria baicalensis,Apricot kernel,Pinellia ternata,Belamcanda chinensis,Platycodon grandiflorus,etc. The drug properties were mainly cold,warm,slightly cold and flat,the flavors of the medicines were bitter,spicy,sweet and slightly bitter,and the meridians involved were mainly the lung,stomach and spleen meridians. The main types of drugs were antipyretic and detoxifying drugs,pharynx?benefiting drugs and wind?heat?dispelling drugs. Four groups of drugs were obtained by cluster analysis,and 6 core drugs were obtained by complex network analysis. Conclusion Professor Chang Ke treats cough mainly based on "restoring the dispersion and descent of lung qi". He is good at using Chinese medicines with the effect of removing heat and toxin, dispelling wind heat, resolving dampness and phlegm and benefiting throat.

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    Application of San Yin Zhi Yi in the treatment of children with cough variant asthma
    LIANG Chaoqi, LONG Hongyan
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 79-83.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.017
    Abstract (2781)      PDF(pc) (1080KB)(2689)       Save
    Pediatric cough variant asthma (CVA) is a common chronic respiratory disease primarily characterized by chronic cough. The exact etiology of CVA is not yet fully understood, but it is widely believed that the progression of the disease is influenced by various pathological factors, and is closely related to the patient's individual constitution, seasonal changes, and regional environmental characteristics. Traditional Chinese medicine (TCM) categorizes CVA under "wind cough", "wheezing cough", and "spasmodic cough", and pediatric CVA is managed according to the principle of "San Yin Zhi Yi"(three-cause adaptation), which involves personalized adjustments of the treatment plan based on the patient's constitution, seasonal changes and regional environment, reflecting the holistic treatment concept and syndrome-differentiation treatment of TCM. Therefore, this article discusses the etiology and pathogenesis of pediatric CVA from the perspectives of both TCM and modern medicine, based on the TCM principle of "San Yin Zhi Yi". It comprehensively considers the impact of factors such as constitution, season and environment on the onset and progression of the disease, exploring the application of San Yin Zhi Yi treatment for pediatric CVA from the three aspects of adapting to the season, region and individual. The aim is to provide a better theoretical foundation and practical guidance for the future TCM treatment of pediatric CVA.
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    Research progress on external treatment of traditional Chinese medicine for children with sleep disorders
    LIU Wen, GUAN Lijun
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 410-413.   DOI: 10.3969/j.issn.1674-3865.2024.05.011
    Abstract (2037)      PDF(pc) (1030KB)(2667)       Save
    Sleep disorders have gradually become one of the common diseases in children,and sleep quality is very important for children′s growth and development.Traditional Chinese medicine has achieved remarkable results in the treatment of sleep disorders in children.Because of its safety,reliability,having no adverse reactions and simple operation,TCM external treatment is easy to be accepted by parents.This paper systematically sorts out the commonly used external treatment methods of Chinese medicine for children with sleep disorders,including acupuncture,acupoint application,massage and transcranial magnetic therapy,etc.,and summarizes and studies the relevant literature of these methods.
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    Clinical application of "Method of regulating spleen to mediate qi movement" in pediatric diseases
    WU Min, PENG Yu, LIU Qiyan, SUN Haipeng, WU Hao, CHEN Yingyu, HUANG Jing
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (2): 142-146.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.02.009
    Abstract (1650)      PDF(pc) (1008KB)(2579)       Save
    The transportation and transformation function of the spleen is based on the normal qi movement of the ascending of the spleen and the descending of the stomach.It needs to interact with the ascending of the liver and the descending of the lung to regulate the qi movement.The normal transportation of the spleen can "mediate" the qi movement of the four viscera and transform essence qi to nourish the five viscera.This article summarizes the entire process of the spleen′s transportation and transformation in four stages:"The stomach accepts and the spleen transports to generate essence,the spleen governs distribution and transformation to refine essence,the lung assists the spleen qi to disperse essence,and the spleen ascends and the intestines descend to transport essence",forming the academic thought of "the spleen governing the four essences".The following processes are further specified and visualized,including the digestion and absorption of food and water by the stomach,the ascending of the clear substances and the descending of the turbid substances by the spleen,and the distribution and transportation of the refined substances of the resulting qi and blood after further processing.Starting from the ascending and descending and pivoting of qi movement in the spleen and stomach,lung and liver,lung and stomach,and liver and spleen,the "method of regulating spleen to mediate qi movement" is used to regulate the ascending and descending functions of qi movement in the spleen and stomach,and liver and lung,and is closely combined with the pathogenesis,disease location,and treatment methods of pediatric diseases,which lays a foundation for its clinical application.The spleen of children is often insufficient in the physiological state,and the spleen and stomach are easily injured by diet,resulting in abnormal ascending and descending of qi movement in the spleen and stomach,so children often have spleen diseases.The "method of regulating spleen to mediate qi movement" includes various treatment methods,such as regulating the spleen to eliminate accumulation,regulating the spleen to eliminate distension,regulating the spleen to soothe the liver and reduce the adverse qi,and regulating the spleen to ventilate the lung and unblock the orifices.It is a comprehensive treatment approach that can quickly restore the transportation and transformation function of the spleen and also promote the recovery of the qi movement through "mediating the four viscera" by the spleen,which provides new ideas and methods for the treatment of pediatric diseases.
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    Clinical observation on acute cough of recurrent respiratory tract infections in children treated by Xingsu powder with modification
    XIONG Jiaxiu, ZHAO Xiaomin
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (6): 523-526.   DOI: 10.3969/j.issn.1674-3865.2023.06.013
    Abstract (974)      PDF(pc) (786KB)(2540)       Save
    Objective To observe the clinical efficacy of Xingsu powder with modification in the treatment of acute cough of recurrent respiratory tract infections(RRTIs) with external evil inducing phlegm and fluid retention.Methods Fracute cough of RRTIs with external evil inducing phlegm and fluid retention were treated in the pediatric outpatient department of the Second Affiliated Hospital of Jiangxi University of TCM,and they were selected and randomly divided into a control group and an observation group,with 54 cases in each group.The control group was given symptomatic treatment with ambroxol oral solution and inhalation of budesonide solution,and on this basis,the observation group was given Xingsu powder with modification.After 6 days of the above treatment,the clinical efficacy,clinical symptom score,adverse reaction and secondary chronic cough of the two groups were compared.Results After treatment,the total clinical efficiency rate of observation group was 96.30%(52/54),higher than that of control group(83.33%,45/54),and the clinical symptom score was significantly reduced compared with that of control group,the difference bring statistically significant(P<0.05);during the treatment,there was no statistical difference in the incidence of adverse reactions between the two groups(P>0.05);the 4-week follow-up showed that the rate of secondary chronic cough in observation group was 11.11%(6/54),lower than that in control group(25.93%,14/54)(P<0.05).Conclusion Xingsu powder with modification can improve the clinical effect,improve symptoms and reduce the rate of secondary chronic cough in children with acute cough of recurrent respiratory tract infections,which is worthy of clinical promotion.om November 2019 to November 2022,108 cases of 
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    Expert consensus on the diagnosis, treatment and efficacy evaluation of pediatric acute rhinosinusitis in integrated traditional Chinese and Western medicine
    Siyuan HU, Qinglong GU, Xuefeng WANG, Fengying QIAO, Rong MA, Daxin LIU, Qiuhan CAI, Yan CHEN
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (5): 369-375.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.05.001
    Abstract (49)   HTML (3)    PDF(pc) (642KB)(2485)       Save

    The consensus has been developed to clarify the integrated traditional Chinese and Western medicine approach to the diagnosis,treatment,and clinical evaluation of pediatric acute rhinosinusitis. The development methods of the consensus included the RAND/UCLA Appropriateness Method,which comprised two rounds of expert questionnaire surveys and one face-to-face expert panel discussion. The main content covers scope,terms and definitions,overview,Western medicine diagnosis,traditional Chinese medicine syndrome differentiation,integrated Chinese and Western treatment,and assessments of therapeutic efficacy and safety. The consensus is intended to provide a practical reference for standardized clinical diagnosis and treatment of pediatric acute rhinosinusitis,offer methodological support for high-quality clinical research,and promote the translation and development of novel Chinese herbal medicines for children.

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    Professor Jia Liujin's experience in treating atopic dermatitis in children based on the theory of "spleen bitterness and dampness"
    Jingnan XUE, Qing YANG, Yan ZHANG, Liujin JIA
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2026, 18 (1): 45-49.   DOI: 10.20274/j.cnki.issn.1674-3865.2026.01.009
    Abstract (1636)   HTML (2)    PDF(pc) (585KB)(2360)       Save

    Summarize Professor Jia Liujin's clinical experience in treating atopic dermatitis in children based on the theory of "spleen bitterness and dampness" in the Inner Classic. He establishes a pathogenesis framework of "dampness-heat as the core and spleen deficiency as the root", believing that the spleen of children is often insufficient and the internal generation of water and dampness is the root cause of the disease. The pathogenesis of this disease is manifested by the long-term accumulation of dampness transforming into heat or the internal generation of heat and the stagnation of dampness and heat. The combination of internal and external pathogenic factors is a factor that makes atopic dermatitis difficult to cure and prone to recurrence. The formation of blood stasis is the result of the long-term evolution of illness. In terms of treatment, Professor Jia advocates "strengthening the spleen to promote transportation, protecting the root cause", "clearing heat and drying dampness throughout the process", and "regulating and nourishing, emphasizing prevention". With "drying spleen with bitterness" as the guiding principle, Liumiao decoction (Atractylodes, Phellodendron amurense, Achyranthes bidentata, Coix seed, honeysuckle, Sophora sophora) is created as the basic formula to clear heat, dry dampness and strengthen the spleen, treating both symptoms and root causes, and flexibly adjusting the formula according to the stages. During the acute stage, add wind-dispelling and anti-itching products; during the chronic stage, supplement with blood-nourishing and blood-activating herbs; always take care of the spleen and stomach. The diagnostic and therapeutic approach of Professor Jia embodies the traditional Chinese medicine characteristics of "strengthening the spleen and drying dampness throughout the process, treating in stages while taking into account both the symptoms and the root causes", providing a new path for the treatment of atopic dermatitis.

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    Chang Ke′s experience in treating tic disorder in children based on wind,fire,phlegm,deficiency and stasis
    ZHANG Xu, SUN Yuan, CHANG Ke.
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (3): 261-264.   DOI: 10.3969/j.issn.1674-3865.2024.03.017
    Abstract (1449)      PDF(pc) (1008KB)(2250)       Save
    The incidence of tic disorder in children has been increasing year by year.The disease is recurrent and often characterized by multiple and comorbid diseases.Although the etiology and pathogenesis of tic disorder in children is caused by exogenous toxin,the root cause is wind,fire,phlegm,deficiency and stasis.Tic disorder has a variety of etiological causes and variable symptoms,and it is not caused by one organ alone,often involving five organs.Professor Chang Ke understands tic disorder in children from wind,fire,phlegm,deficiency and stasis.In view of its pathogenesis,he uses common and self-created prescriptions to treat it,and the clinical efficacy is very good.Now the treatment experience is summarized as follows,with a case attached.
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    Progress in the clinical features and treatment of pediatric heart failure
    ZHAO Qi, SUN Shuna
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2023, 15 (6): 494-499.   DOI: 10.3969/j.issn.1674-3865.2023.06.007
    Abstract (860)      PDF(pc) (861KB)(2167)       Save
    Heart failure is a clinical syndrome caused by structural or functional abnormalities of the heart,which result in limited cardiac contraction and/or filling,and cardiac output cannot meet the body′s demand.Heart failure is one of the common critical diseases in children.Since all organs of children are not yet mature,if heart failure cannot be corrected,all organs are more likely to be damaged,leading to complications and sequelae,which not only seriously jeopardize children′s lives and health,but also bring heavy medical burden to families and society due to difficulty in treatment and poor prognosis.The etiology,pathophysiological characteristics,and treatments of heart failure in children are very different from those of adult heart failure.The main cause of heart failure in children is congenital cardiovascular abnormalities,while other causes include myocarditis,cardiomyopathy,and coronary artery abnormalities.Adrenergic receptor expression levels,miRNA profiles,and expression of genes associated with myocardial abnormalities differ between children and adults.The treatment for heart failure in children includes etiologic treatment,pharmacotherapy,cell-based therapy,and auxiliary device therapies.Treatment and long-term management regimens for heart failure in children are more challenging than those in adults.This article will review the epidemiology,etiology,pathophysiological features,and treatment of heart failure in children.
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    Exploring the TCM mechanism of tic disorder based on liver and Shaoyang constitution in children
    LIU Ying, ZHONG Mingxiu, SONG Bangguo, ZHANG Di
    Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (3): 265-269.   DOI: 10.3969/j.issn.1674-3865.2024.03.018
    Abstract (1421)      PDF(pc) (1028KB)(2165)       Save
    The onset of tic disorders starts in childhood and adolescence,belonging to neuropsychiatric disorders.With the development of society and the increase of external stimulation,the cases of this disease also have a trend of increase year by year.The whole process of children′s development reflects the characteristics of the liver,and children′s constitution conforms to the characteristics of the liver:if liver qi is peaceful and liver blood is sufficient,children are in normal development;if liver yang is excessive,liver yin is deficient,or liver and kidney do not coordinate,liver wind moves inside,and the symptoms of tic disorders appear.In addition,the improper management of external stimuli results in liver qi stagnation,which also produces internal changes.Based on this,the physiological characteristics of the liver and children′s physical characteristics are taken into account to explore the relationship between the two as well as the connection between the liver and other viscera,and to analyze tic disorders from the perspective of the relationship between the liver and Shaoyang constitution.The following measures has a certain guidance in the treatment of initial and prolonged difficult tic disorder:taking the liver as the main point,regulating the five organs and combining the internal treatment with external treatment together.
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