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Expert consensus on external treatment for tic disorder in children with traditional Chinese medicine(2024) Wang Xuefeng, Han Xinmin, Sun Kexing, Jiang Yonghong, Rong Ping Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (1): 1-7.   DOI: 10.3969/j.issn.1674-3865.2024.01.001 Abstract （4444）      PDF（pc） （1087KB）（1794）       Knowledge map    Save Tic disorder is one of the most common neuropsychiatric diseases in children in clinical practice, which does great harm to children's physical and mental health. External therapy with traditional Chinese medicine, represented by acupuncture and massage, has some special advantages in the treatment of tic disorder in children, but it needs to be further standardized. This consensus covers the terms and definitions of tic disorder in children, the diagnosis, etiology and pathogenesis, syndrome differentiation and technological standards of external therapy with traditional Chinese medicine, and summarizes the modern medical experience and the advances in evidence-based medicine of this disease. This consensus highlights the clinical practicality and reflects the latest research progress, which helps to improve the level of clinical standardization of external therapy for tic disorder in children with traditional Chinese medicine. Related Articles | Metrics

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Talk about the important acupoint in point pressing method of Zangfu diagram——Lanmen acupoint DU Junwei, HOU Xiugang, SUN Xiaojun, CHENG Hongyun Chinese Pediatrics of Integrated Traditional and Western Medicine    2018, 10 (2): 122-124.   DOI: 10.3969/j.issn.1674-3865.2018.02.009 Abstract （4093）      PDF（pc） （387KB）（968）       Knowledge map    Save Point pressing method of Zangfu diagram is a therapy， which can regulate the viscera Qi and restore the viscera function according to the meridian acupoints and viscera parts by using acupuncture method. Lanmen acupoint is the main point of the abdomen and Ren channel. No matter what kind of disease it is， this point must be cleared first. Lanmen acupoint is an iconic character of point pressing method of Zang fu diagram as a hinge guiding Qi downward. Related Articles | Metrics

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Individualized intervention strategies in the treatment of childhood and adolescent obesity based on precision medicine LI Ping, YANG Fan, LIU Hanmin Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 1-7.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.001 Abstract （3654）      PDF（pc） （1165KB）（4874）       Knowledge map    Save Childhood and adolescent obesity has become a global challenge in public health.Its high weight regain rate and risks of metabolic complications highlight the limitations of traditional intervention strategies.This review systematically explores individualized intervention strategies for obesity in children and adolescents in the context of precision medicine,breaking the traditional "one-size-fits-all" model.It integrates multi-omics technologies with intelligent management methods,proposing a multidimensional framework for precise intervention.First,a precise diagnosis and evaluation system is constructed based on multi-modal data,including genomics,radiomics,and gut microbiomics,to identify genetic susceptibility,metabolic phenotypes and microbiome characteristics,laying the foundation for stratified interventions.Secondly,individualized intervention plans are developed based on genetic risk scores,epigenetic regulatory mechanisms,and gut microbiome-targeted therapies:gene-guided strategies aim to optimize dietary structure through multi-gene risk assessments; epigenetic interventions aim to regulate DNA methylation and histone modification by taking advantage of nutrients (such as methyl donors and short-chain fatty acids),reversing metabolic dysregulation; microbiome remodeling aims to improve energy metabolism balance through probiotics and synbiotics.Furthermore,artificial intelligence and wearable devices are employed for dynamic monitoring in multiple scenarios.By collaborating with multidisciplinary teams in nutrition,sports medicine,and psychology,a smart management model of "hospital-family-community" network is established.While precision medicine offers groundbreaking directions for childhood obesity treatment,challenges such as biomarker validation,data integration,and long-term efficacy evaluation remain to be addressed.This review provides theoretical foundations and practical pathways for the improvement in the effectiveness and sustainability of interventions,emphasizing the need to integrate interdisciplinary innovative technologies in the future in order to promote the transformation of childhood obesity management toward precision and intelligence. Related Articles | Metrics

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Effect of ambroxol hydrochloride combined with procaterol hydrochloride in the treatment of children with pneumonia MA Zhongxia Chinese Pediatrics of Integrated Traditional and Western Medicine    2016, 8 (3): 327-329.   DOI: 10.3969/j.issn.1674-3865.2016.03.027 Abstract （3465）      PDF（pc） （357KB）（247）       Knowledge map    Save Objective: To summarize the clnical effect of ambroxol hydrochloride Combined with procaterol hydrochloride in the treatment of children with pneumonia.Methods: A total of 150 children with pneumonia were chosen and were divided into two groups according to their admission number:the control group and the observation group.The control group was given routine treatment,while The observation group was treated with ambroxol hydrochloride in combination with procaterol hydrochloride|the treatment course was 14 days for both groups.At the end of the course,the clinical effect was compared between the two groups.Results: The total effective rate in the observation group was significantly higher than the control group with statistical differnce(P< 0.05)|the rate of adverse reactions was obviously lower in the observation group than in the control group,the difference being of statistical significance(P<0.05).Conclusion: Ambroxl hydrochloride combined with procaterol hydrochloride has good effect and fewer adverse reactions in the treatment of children with pneumonia,and it can improve the prognosis of these children,which is worthy of popularization. Related Articles | Metrics

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Traditional Chinese medicine constitution analysis of children with attention deficit hyperactivity disorder (syndrome of heart and liver fire hyperactivity) ZHOU Min, WANG Minhua, LI Yaqun Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 54-58.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.011 Abstract （3149）      PDF（pc） （1113KB）（2084）       Knowledge map    Save Objective To explore the distribution of traditional Chinese medicine(TCM) constitution in children with attention deficit hyperactivity disorder(ADHD) (syndrome of heart and liver fire hyperactivity),and its relationship with symptoms and social function of the children.Methods A total of 70 children aged 7 to 14 years with ADHD (syndrome of heart and liver fire hyperactivity) were included in the study,who were treated in Yixing Traditional Chinese Medicine Hospital from January 2023 to May 2024.The TCM syndrome scoring,SNAP-Ⅳ and CGAS were used to evaluate the severity of the symptoms and the impact on social function of the children,and the TCM constitution distribution was divided according to the TCM constitution scale.Results TCM syndrome score was (18.54 ± 2.84) in ADHD children (syndrome of heart and liver fire hyperactivity).The average SNAP-Ⅳ score of the boys was (41.02±8.56),the average SNAP-Ⅳ score of the girls was (41.19±8.46),the average CGAS score of the boys was (63.12±6.83),and the average CGAS score of the girls was (63.75±6.65),which significantly affected the children′s social function and normal life activities; the severity of the disease was not related to gender(P>0.05).Unbalanced constitution was the main type of TCM constitution,totaling 42 cases (60%),and 28 cases (40%) were with balanced constitution.Among the children with unbalanced constitutions,the number of children with qi-stagnation constitution,yin-deficiency constitution and qi-deficiency constitution was the highest (≥10%); the children with yin-deficiency constitution had the longest course of disease ［(4.25±0.41) years］,and the children with balanced constitution had the shortest course of disease ［(1.74±0.33) years］.Conclusion The TCM syndrome score of the 70 children with ADHD(syndrome of heart and liver fire hyperactivity) in Yixing area included in this study is high,which has a significant impact on the social function of the children,but there is no gender difference.Unbalanced constitution is the main type in the distribution of constitution,and the disease course of ADHD (syndrome of heart and liver fire hyperactivity) is different in children with different constitutions. Related Articles | Metrics

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Research progress in causes of premature puberty in traditional Chinese and western medicine LIU Qiannan, WANG Yanchao, MIAO Yizhuo, LI Lan Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 13-16.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.003 Abstract （3140）      PDF（pc） （1085KB）（662）       Knowledge map    Save Since the 1970s,it has been believed in traditional Chinese medicine (TCM) that the pathogenesis of precocious puberty is primarily associated with yin-deficiency and fire-excess,and the treatments that nourish yin and purge fire are advocated.Therefore,an integrated treatment strategy combining TCM and western medicine has gradually been formulated.Modern medical research indicates that precocious puberty results from the interplay of genetic and environmental factors,involving heredity,diet,chemical substance interference,and psychological factors.TCM emphasizes the combined influence of internal and external factors,such as dietary irregularities and emotional disturbances,and focuses on therapeutic methods like nourishing yin,purging fire,soothing the liver,and relieving stagnation.The integrated approach of TCM and western medicine offers a more comprehensive treatment plan for precocious puberty.The TCM theory of "preventive treatment of disease" underscores the importance of prevention,reducing risk factors and performing proactive treatment to avoid long-term complications. Related Articles | Metrics

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Guidelines for the diagnosis and treatment of influenza in children with integrated traditional Chinese and western medicine WANG Xuefeng, WANG Lining, DENG Li, LIU Hanmin, SHANG Yunxiao, ZHANG Baoqing, ZHAO Shunying Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (2): 93-101.   DOI: 10.3969/j.issn.1674-3865.2024.02.001 Abstract （3124）      PDF（pc） （1052KB）（1031）       Knowledge map    Save Children are the high incidence population of influenza and the high risk population of severe cases.Early intervention of influenza,especially the intervention with traditional Chinese and western medicine in the mild stage,is of great significance to the prognosis of the disease.Based on the development process of literature retrieval and evaluation,expert interview,group discussion,expert demonstration meeting and public consultation,the guidelines for the diagnosis and treatment of influenza in children with integrated traditional Chinese and western medicine are formed.This version of the guidelines includes the scope of application,normative reference documents,terms and definitions,diagnosis and treatment,aiming to provide an important reference for the clinical practice,diagnosis and treatment norms and quality evaluation of the treatment with integrated traditional Chinese and western medicine for children with influenza. Related Articles | Metrics

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Experience in the diagnosis and treatment of children's diseases from "accumulated internal heat" ZHANG Yu, XIAO Yang, ZHOU Mengxiao, SUN Liping Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 59-63.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.012 Abstract （2941）      PDF（pc） （1073KB）（6641）       Knowledge map    Save The function of the spleen in children is often insufficient, and improper feeding, or disease damage may cause the fact that food can't be digested, which is food accumulation。Although it is a disease of the spleen, Professor Sun Liping believes that long time of food accumulation can form internal heat syndrome, thereby inducing a variety of pediatric diseases. Attention should be paid to the physical changes caused by congenital abnormality and acquired dystrophy. Based on the physiological and pathological characteristics of children, Yin and Yang theory, five-element theory and constitution theory, and through combination with more than 30 years of clinical experience of Professor Sun Liping, this paper explores the etiology and pathogenesis of children's diseases caused by "food", the disease outcome transformed by "heat", the diagnosis experience from "observation", and the treatment method by "elimination". A new line of thinking of "same treatment for different diseases" is provided for the diagnosis and treatment of abdominal pain, cough, asthma and tic disorders caused by food accumulation. Related Articles | Metrics

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Research on the clinical application of Zhimu-Huangbai in precocious puberty CHEN Na, LI Lianke, LU Yihong, YANG Yang, TAO Qiong, CHEN Zhu Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 8-12.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.002 Abstract （2938）      PDF（pc） （1083KB）（643）       Knowledge map    Save Zhimu-Huangbai is a commonly used medicine pair in clinical practice,and the compatibility of the two drugs has the effects of nourishing yin and clearing heat,purging fire and detoxifying.Modern studies have found that Zhimu-Huangbai has anti-inflammatory,antioxidant,hypoglycemic,and lipidemic regulation effects because of its main active ingredients such as quercetin,kaempferol,barmatine,stigmasterol,mangiferin,berberine,etc.It is widely used in clinical practice,mainly for the treatment of precocious puberty,diabetes,diabetic nephropathy and other diseases in children.From the perspectives of chemical composition,pharmacological effects and clinical application,this paper expounds the application research of Zhimu-Huangbai in precocious puberty in recent years,in order to provide a theoretical basis for the scientific application of the drug in precocious puberty and for the research and development of new drugs. Related Articles | Metrics

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Clinical effect of Xiaoer Kechuanling granules combined with ambroxol hydrochloride oral liquid on children with bronchopneumonia HUANG Zhanke, LI Weili, CAI Ming Chinese Pediatrics of Integrated Traditional and Western Medicine    2016, 8 (3): 304-306.   DOI: 10.3969/j.issn.1674-3865.2016.03.018 Abstract （2908）      PDF（pc） （359KB）（236）       Knowledge map    Save Objective: To study the effect of Xiaoer Kechuanling granules combined with ambroxol hydrochloride oral liquid on children with bronchopneumonia.Methods: From May 2013 to Apr.2015,a total of 80 children with bronchopneumonia who accepted treatment in our hospital were taken as the clinical research objects,and these patients were randomly divided into observation group(40 cases)and control group(40 cases).Patients in these two groups all accepted conventional therapy|in addition,patients in the control group were given ambroxol hydrochloride oral liquid,and the other patients in the observation group were given both ambroxol hydrochloride oral liquid and Xiaoer Kechuanling granules.Five days after treatment,we observed and compared their clinical effects and symptom relief time.Results: The total effective rate of the observation group was significantly higher than that of the control group(P<0.05)|the fever regression time and disappearance time of cough,wheezing and rale of the observation group were all less than those of the control group,and the differences between them were statistically significant(P<0.05).Conclusion: Xiaoer Kechuanling granules combined with ambroxol hydrochloride oral liquid,which has good clinical effect on children with bronchopneumonia,can effectively relieve their clinical symptoms.Thus,it is worthy of promotion. Related Articles | Metrics

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Treatment for pediatric pulmonary diseases based on the theory of "lungs governing skin and hair" and the method of "analogy and classification"  WEI Jiaxuan, YANG Jianhui, FENG Zhongfa, LI Rong, ZHAO Shun, LIU Qiaoya Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 75-78.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.016 Abstract （2887）      PDF（pc） （1062KB）（3305）       Knowledge map    Save This paper explores the application value of Traditional Chinese Medicine (TCM) theory of "lungs governing skin and hair" and the thinking method of "analogy and classification" in the treatment of pediatric pulmonary diseases.Both "lungs governing skin and hair" and "analogy and classification" are traditional TCM theoretical approaches guiding clinical differential diagnosis and treatment.By discussing the correlation between the lungs and the skin and hair,and then employing the method of analogy and classification,this paper explores the feasibility and efficacy of treating pulmonary diseases by the "skin"-cortex (the character of skin and cortex is the same in Chinese).Starting from the physiological characteristics of children,such as "lung deficiency" and loose cutaneous layers,the paper argues that "cortex-related" herbal medicines (e.g.,Baixian Pi,Hou Po,and Chan Tui) can improve the pathological features of being easily invaded by external pathogens in children.Through case studies,this paper demonstrates a formula containing cortex-related herbs in the treatment of cough (wind-phlegm obstructing the lung) in a 4-year-old child,which is very effective.The results confirm the clinical feasibility of this approach.By integrating traditional TCM theories with modern scientific validation,this paper provides new insights into the diagnosis and treatment of pediatric pulmonary diseases,highlighting the unique advantages of TCM in the field of pediatrics. Related Articles | Metrics

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Experience and reflection on traditional Chinese medicine treatment for precocious puberty in children and impaired height XIONG Lei, HE Xiying, CAO Ting Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (5): 377-379.   DOI: 10.3969/j.issn.1674-3865.2024.05.003 Abstract （2851）      PDF（pc） （1016KB）（1065）       Knowledge map    Save The clinical manifestation of precocious puberty is the premature development of secondary sexual characteristics, which can cause increased growth rate, rapid skeletal maturation, premature epiphyseal closure, etc. If not treated in time, it may cause children to be short in adulthood and increase the risk of endocrine diseases. Gonadotrophin releasing hormone analogue is the first choice in the treatment of this disease in western medicine, which can significantly inhibit the sexual development process by regulating the hypothalamic pituitary gonadal axis, but there is still controversy in terms of benefits to children's height. Traditional Chinese medicine therapy has been proven to be safe and effective in improving children's symptoms, regulating sex hormone levels, delaying gonadal development, improving height impairment, and increasing adult height. Professor Xiong Lei believes that the core pathological mechanism of this disease is kidney yin deficiency and hyperactivity of liver yang fire. The treatment should be nourishing yin to strengthen the root, and lowering fire to clear sources. At the same time, for the patients with stagnated heat of liver channel, the method of dispersing stagnatedliver qi and clearing fire is used; for those with internal retention of phlegm dampness, the method of invigorating spleen to dissipate phlegm is used; for those with disharmony in the middle jiao, the method of invigorating spleen and harmonizing stomach is used. For children with rapid progression, gonadotrophin releasing hormone analogue can be used at the same time; for children with growth retardation and height impairment, recombinant human growth hormone should be considered to maximize their benefits to the height. Related Articles | Metrics

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Current research status of the influence of dietary patterns on precocious puberty in children LIU Ziqi, ZHANG Guiju Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 17-22.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.004 Abstract （2833）      PDF（pc） （1129KB）（1334）       Knowledge map    Save When children enter puberty,they will experience prominent changes mainly in the morphology of their reproductive organs,and development of function and secondary sexual characteristics.The main manifestation of precocious puberty is the earlier development of secondary sexual characteristics and the premature maturation of sexual organs,which is an endocrine disease characterized by abnormal growth and development of children.With the development of economy and society,the advancement of the onset age of precocious puberty and the increase in incidence rate have triggered increasing social attention.Multiple factors can have an impact on precocious puberty,and modern researches have confirmed a correlation between the daily diet of children before puberty and precocious puberty.This article reviews domestic and foreign researches in common dietary patterns and various dietary nutrients related to adolescent sexual development in children,represented by high calorie diet patterns,Mediterranean diet patterns,and vegetarian diet patterns,and it summarizes the influence of different dietary patterns on precocious puberty in children.The article respectively summarizes the potential regulatory mechanisms of high protein diet,high-fat diet and high sugar diet in high calorie diet patterns,as well as the main dietary components (vegetables,fruits,olive oil,grains,nuts,beans,and dairy products) in Mediterranean diet patterns and vegetarian diet patterns in sexual development.The aim is to provide theoretical basis for the prevention and treatment of precocious puberty in children from the perspective of dietary intervention,and to provide new ideas for future researches on the relationship between dietary nutrition structure and sexual development. Related Articles | Metrics

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Analysis of risk factors for hyperuricemia in children of different ages FANG Yanying, GAN Jiahui, XU Yuyin, XU Ziying, SITU Meiling, YU Shujuan Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 45-49.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.009 Abstract （2825）      PDF（pc） （1099KB）（467）       Knowledge map    Save Objective To measure serum uric acid(SUA) levels in children of different ages(0 to 14 years),investigate the incidence of high level of uric acid in those regions,and analyze its association with gender,age,body size-body mass index(BMI),and living habits［including consumption of seafood,consumption of long-boiled soup/stew,consumption of vegetables,consumption of beverages,consumption of sweets,daily water intake(mL) and daily exercise (min)］.Methods Totally 1 209 children visiting Kaiping City Centre Hospital and Kaiping Maternal and Child Health Hospital from January 2022 to September 2023 were enrolled in the study.Height/length,weight and SUA of the children were measured,and the children were grouped according to age and gender in order to investigate the SUA levels of children in different age groups and genders.In addition,the children were grouped according to the SUA level to investigate the current situation of uric acid and the incidence of hyperuricaemia in the region.In the meantime,the relationship between hyperuricaemia(HUA) in the children and their gender,age,body size-BMI and living habits were also investigated.Results The distribution of SUA levels showed no statistically significant difference between different genders(P>0.05). In children of different ages and body types, SUA levels exhibited a trend of gradual increase with age and body type growth. The overall detection rate of hyperuricemia was 20.18%(244/1 209), and the comparison of the detection rates of hyperuricemia between different genders showed no statistically significant difference(P>0.05). However, the comparison of hyperuricemia detection rates among different ages and body types showed statistically significant differences(P<0.01). Logistic regression analysis revealed that seafood consumption, beverage intake, and a preference for sweet foods were risk factors for hyperuricemia, while increased vegetable intake, fluid consumption, and appropriate exercise were protective factors for uric acid levels. Conclusion The level of SUA in children in Kaiping City increases with age and changes in body type, with no specific relation to gender; high-purine and high-sugar foods are risk factors for hyperuricemia. Related Articles | Metrics

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Diagnosis and treatment guideline for functional dyspepsia in children with the integrated traditional Chinese and western medicine WANG Xuefeng, WU Jie, GONG Sitang, XIONG Lei, JIANG Mizu, WANG Baoxi, XU Hua, PENG Yu Chinese Pediatrics of Integrated Traditional and Western Medicine    2024, 16 (6): 461-468.   DOI: 10.3969/j.issn.1674-3865.2024.06.001 Abstract （2813）      PDF（pc） （1049KB）（1400）       Knowledge map    Save Functional dyspepsia,as one of the most common functional diseases of upper digestive tract,seriously affects the quality of life and growth and development of children in China.Due to the changing definition and symptom spectrum of functional dyspepsia in children,its diagnosis and treatment are controversial.In order to standardize the diagnosis and treatment of children with functional dyspepsia with integrated traditional Chinese and western medicine,and effectively solve the clinical problems in the diagnosis and treatment of children with functional dyspepsia,this guideline is formulated to guide the standardized diagnosis and treatment of children with functional dyspepsia with integrated traditional Chinese and western medicine. Related Articles | Metrics

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Clinical curative effect of Xiaoer Feike granule combined with Ambrocol oral solution on infantile bronchitis WEI Wei, LI Ting, GUO Tiejian, ZHANG Chengying Chinese Pediatrics of Integrated Traditional and Western Medicine    2018, 10 (1): 53-55.   DOI: 10.3969/j.issn.1674-3865.2018.01.015 Abstract （2801）      PDF（pc） （419KB）（312）       Knowledge map    Save Objective:To investigate clinical curative effect of Xiaoer Feike granule combined with Ambrocol oral solution on cough caused by bronchitis in children.Methods:A total of 89 children with cough caused by the bronchitis, treated between Oct. 2014 and Jun. 2015 in Dalian Municipal Women and Children's Medical Center, were randomly divided into observation group(46 cases) and control group(43 cases). Both groups were given conventional treatment, and the observation group was additionally treated by Xiaoer Feike granule combined with Ambrocol oral solution, 7 d for a course of treatment, and finally we analyzed and compared the clinical curative effect and cough suppressant time of the two groups.Results:The total effective rate of observation group was 93.5%（43/46）, significantly higher than that of control group 79.1% (34/43), and the difference was statistically significant(P<0.05). The cough suppressant time of observation group was (4.32±2.79)d, significantly lower than that of the control group (6.03±3.82)d, and the difference was statistically significant(P<0.05). There were no obvious adverse reactions in the process of clinical treatment.Conclusion:he cough caused by bronchitis can be effectively controlled by Xiaoer Feike granule combined with Ambrocol oral solution. Related Articles | Metrics

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Application of San Yin Zhi Yi in the treatment of children with cough variant asthma LIANG Chaoqi, LONG Hongyan Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 79-83.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.017 Abstract （2781）      PDF（pc） （1080KB）（2689）       Knowledge map    Save Pediatric cough variant asthma (CVA) is a common chronic respiratory disease primarily characterized by chronic cough. The exact etiology of CVA is not yet fully understood, but it is widely believed that the progression of the disease is influenced by various pathological factors, and is closely related to the patient's individual constitution, seasonal changes, and regional environmental characteristics. Traditional Chinese medicine (TCM) categorizes CVA under "wind cough", "wheezing cough", and "spasmodic cough", and pediatric CVA is managed according to the principle of "San Yin Zhi Yi"(three-cause adaptation), which involves personalized adjustments of the treatment plan based on the patient's constitution, seasonal changes and regional environment, reflecting the holistic treatment concept and syndrome-differentiation treatment of TCM. Therefore, this article discusses the etiology and pathogenesis of pediatric CVA from the perspectives of both TCM and modern medicine, based on the TCM principle of "San Yin Zhi Yi". It comprehensively considers the impact of factors such as constitution, season and environment on the onset and progression of the disease, exploring the application of San Yin Zhi Yi treatment for pediatric CVA from the three aspects of adapting to the season, region and individual. The aim is to provide a better theoretical foundation and practical guidance for the future TCM treatment of pediatric CVA. Related Articles | Metrics

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Clinical effect of recombinant human interferon α-2b spray on herpangina in children YAO Tingxin, LIAO Yinan, GU Fen, YU Sijing, YIN Fei Chinese Pediatrics of Integrated Traditional and Western Medicine    2017, 9 (5): 427-429.   DOI: 10.3969/j.issn.1674-3865.2017.05.020 Abstract （2764）      PDF（pc） （425KB）（1084）       Knowledge map    Save Objective:To evaluate the efficacy and safety of recombinant human interferon α-2b(IFN α-2b) spray on herpangina in children, in order to provide scientific evidence for proper administration in pediatrics.Methods:A total of 122 children with herpangina at Hunan Children's Hospital and Xiangya Hospital were randomly assigned to two groups: the control group(n=61) treated with ribavirin and conventional therapy,and the observation group(n=61) treated with recombinant human IFN α-2b spray and conventional therapy．The clinical efficacy was evaluate．Results:The total clinical effective rate of the observation group was 80.3%（49/61）,significantly higher than the control group(63.9%,49/61）. The defervescence time，oral and pharynx herpes disappearance time and the eating-recovery time in observation group were significantly shorter than those in control group(P<0.05).During the treatment, there were no adverse drug reactions in both groups.Conclusion:Recombinant human interferon α-2b spray has significant effect and safety, which can significantly improve the fever course of children with herpangina and shorten the herpes disappearance time and eating-recovery time; there is no adverse reaction. Related Articles | Metrics

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Analysis of the current status of clinical practice guidelines and diagnosis and treatment norms for children with pneumonia in recent 20 years WANG Bo, XIONG Lei, WANG Ziwei, BIAN Ji, YANG Shaoying, HE Xiying, MING Xi Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 39-44.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.008 Abstract （2738）      PDF（pc） （1291KB）（570）       Knowledge map    Save By searching CNKI, China biomedical literature service system, Wanfang data knowledge service platform, Weipu Chinese science and technology journal full-text database, Pubmed, Embase and other databases, as well as Yimaitong, NICE,NGC,GIN and other websites, clinical practice guidelines and diagnosis and treatment norms for pediatric pneumonia were sorted out, and literature was independently screened by researchers. After extracting the data, the AGREE Ⅱ tool is used to evaluate the quality of the formulation methodology of the guidelines and diagnosis and treatment norms, and the recommended level is obtained, in order to grasp the formulation methods and quality status of clinical practice guidelines for childhood pneumonia at home and abroad, and to provide reference for the future formulation of high-quality clinical practice guidelines in professional fields. Related Articles | Metrics

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Analysis of the development of treatment for pediatric rhinitis from the perspectives of deficiency and cold syndromes and the application of Xu's pediatrics theory of supporting yang CUI Chen, LI Jingwei, ZHOU Junhui, YANG Chuwen, ZHAO Jun, PU Xiaowei Chinese Pediatrics of Integrated Traditional and Western Medicine    2025, 17 (1): 67-70.   DOI: 10.20274/j.cnki.issn.1674-3865.2025.01.014 Abstract （2695）      PDF（pc） （1054KB）（363）       Knowledge map    Save Pediatric rhinitis is a common nasal disorder in children. TCM practitioners throughout history have extensively discussed its etiology and pathogenesis. This article traces the literature and historical origins of treatment for pediatric rhinitis from the perspectives of deficiency and cold syndromes. It is pointed out that external cold is a common cause. The root cause of its recurrence is the deficiency and damage of the lungs, spleen and kidneys. The pathogenesis involves lung-qi deficiency and coldness, leading to insufficient defense of the exterior; kidney-yang deficiency results in a lack of warmth and nourishment; spleen and stomach weakness leads to the failure of ascending clear yang; all of the above factors contribute to the development of pediatric rhinitis. Additionally, the article delves into Xu's pediatrics theory of supporting yang and its application, aiming to provide assistance for clinical practice. Related Articles | Metrics