Abstract: Objective:To observe the clinical effect of integrated traditional Chinese and Western medicine and early rehabilitation training in the treatment of neonatal hypoxic ischemic encephalopathy.Methods:Totally 152 cases of hypoxic ischemic encephalopathy were randomly divided into treatment group and control group, 76 cases in each group. In the early stage, oxygen inhalation, sedation, dieresis, intracranial pressure reduction, control of seizures and other symptomatic support therapies were given in both of the groups. In the stable stage, patients in the control group were given cerebroprotein hydrolysate for injection and monosialo four hexose ganglioside injection. In the treatment group, besides cerebroprotein hydrolysate for injection and monosialo four hexose ganglioside injection, patients were given traditional Chinese medicine treatment based on pattern differentiation and early rehabilitation training. NBNA was performed on 3 d,14 d and 28 d respectively and compare the NBNA of the two groups before and after treatment. Intelligence development was determined respectively at 3,6,9,12 and 18 months. Observe and compare the clinical effect in the two groups after treatment.Results:The total effective rate was 92.1% in the treatment group, and 78.9% in the control group, the difference of which was statistically significant (P<0.05).The NBNA was significantly improved in the two groups after treatment, and the difference was of statistical significance(P<0.05). The NBNA was higher in the observation group than in the control group with statistical difference(P<0.01). After treatment the development score was significantly improved in both groups, and there was statistical difference compared with that before treatment(P<0.01),the score improvement was more significant in the observation group,the difference being statistically significant(P<0.01).Conclusion:The combination of traditional Chinese and Western medicine and early rehabilitation training is effective in the treatment of neonatal hypoxic ischemic encephalopathy.

Key words: Integrated medicine, Early rehabilitation training, Neonatal hypoxic ischemic encephalopathy, Baby,newborn