Abstract: Objective: To observe the effect of Bushen Gubiao prescription combined with Huangqin Kechuan plaster powder in the treatment of children with recurrent respiratory infection.Methods: A total of 90 children with recurrent respiratory infection, who visited  Shanghai TCM Hospital between May and July of 2015, were collected and they were randomly divided into 3 groups: internal treatment group(A), external treatment group(B) and combined internal and external treatment group(C), 30 children in each group. Group C was given Bushen Gubiao prescription combined with Huangqin Kechuan plaster powder for treatment; group B was treated with Huangqin Kechuan plaster powder in summer; group A was given Bushen Gubiao prescription for internal taking. The treatment lasted for 6 weeks. Observe the daily symptom scores of the children before and after treatment and the clinical effect; detect the sIgA level abnormalities in the saliva of children.Results: The clinical effective rate was 56.7%(17/30) in group C, which was significantly higher than that in group B(16.7%,5/30) and group A(23.3%,7/30), with statistical difference(P<0.017). In the treatment of abnormal diet and abnormal bowel movement, the daily symptom scores of group B were higher than those of group C and group A, with statistical difference(P<0.05); in the treatment of abnormal sweating, the scores of group C were lower than group A and B, and there was statistical difference(P<0.05). The rate of abnormal saliva sIgA in group C was 54.2%(13/24), significantly lower than that of group B(90.5%,19/21), the difference being significantly statistical(P<0.017).Conclusion: Internal treatment with Bushen Gubiao prescription, external treatment with Huangqin Kechuan plaster powder, and the combined treatment of the above two are all effective in recurrent respiratory infection, and the combined therapy is better than the other two therapies

Key words: Recurrent respiratory infection, Bushen Gubiao prescription, Huangqin Kechuan plaster powder, Clinical observation, Chidren