ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (2): 222-224.doi: 10.3969/j.issn.1674-3865.2016.02.033

• 调查研究 • 上一篇    下一篇

济南地区冬季肺炎患儿呼吸道病毒感染情况分析

郑彬茹，张葆青   

  1. 250014 济南，山东中医药大学第一临床医学院(郑彬茹)；山东中医药大学附属医院儿科(张葆青)
  • 收稿日期:2015-06-15 出版日期:2016-04-25 上线日期:2016-04-25
  • 通讯作者: 张葆青，E-mail：baoqing09009@126.com
  • 作者简介:郑彬茹(1990-)，女，山东中医药大学2013级硕士研究生在读。研究方向：小儿呼吸系统疾病的研究

Analysis of viral infection of respiratory tract in children with pneumonia in Ji′nan area in winter

ZHENG Binru，ZHANG Baoqing   

  1. The First Clinical Medical College of Shandong University of Traditional Chinese Medicine，Ji′nan 250014，China.
  • Received:2015-06-15 Published:2016-04-25 Online:2016-04-25
  • Contact: ZHANG Baoqing，E-mail：baoqing09009@126.com

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摘要： 目的：了解济南地区冬季肺炎住院患儿呼吸道病毒感染情况，为临床诊断、治疗提供依据。方法：采集208例2014年12月至2015年2月山东中医药大学附属医院诊为支气管肺炎的住院患儿病历资料，取患儿鼻腔内分泌物，以直接免疫荧光法检测常见的呼吸道病毒，包括呼吸道合胞病毒、腺病毒、流感病毒A、流感病毒B及副流感病毒。结果：208例患儿中男性感染率为68.47%(76/111)，女性感染率为67.01%(65/97)，不同性别感染率比较差异无统计学意义(P>0.05)。在208例肺炎患儿中呼吸道病毒感染者141例(67.79%)，其中单种病毒感染56例(39.71%)，2种及2种以上病毒感染85例(60.29%)；呼吸道合胞病毒、流感病毒A感染率最高。<3岁患儿感染率为77.42%(48/62),3~6岁61.42%(78/127),>6岁78.94%(15/19)。结论：呼吸道合胞病毒、流感病毒A是济南地区冬季肺炎患儿感染的主要病原体。

关键词: 肺炎, 呼吸道病毒, 感染, 儿童

Abstract: Objective:To investigate the respiratory virus infection in hospitalized children with pneumonia in Ji′nan area in order to provide evidence for clinical diagnosis and treatment.Methods:From December 2014 to February 2015 in the Affiliated Hospital of Shandong University of Traditional Chinese Medicine,the clinical data of 208 hospitalized children with bronchial pneumonia were collected.The common respiratory tract virus was detected by direct immunofluorescence assay in the nasal secretions of the patients,including respiratory syncytial virus,adenovirus,influenza virus and parainfluenza virus.Results:The male infection rate was 68.47%(76/111)in 208 cases,and the female infection rate was 67.01%(65/97).The difference was not statistically significant(P>0.05).In 208 cases of bronchial pneumonia children,respiratory virus infection occurred in 141 patients(67.79%),in which there was single virus infection in 56 cases(39.7%),2 or more than 2 kinds of virus infection in 85 cases(60.29%);the infection rate of respiratory syncytial virus and influenza A was the highest.The infection rate was 77.42%(48/62)in children under 3 years old,61.42%(78/127)in children aged 3 to 6 years,and 78.94%(15/19)in children over 6.Conclusion:Respiratory tract virus and influenza virus A are the main pathogen of infection in children with pneumonia in Ji′nan area.

Key words: Pneumonia, Respiratory virus, Infection, Children