Abstract: Objective：To analyze the relevant risk factors of cerebral palsy(CP) and provide a reference for the prevention of the disease.Methods：The 50 children with cerebral palsy hospitalized in Pediatric Rehabilitation Center from October 2013 to March 2015 were studied as observation group.The 100 healthy children were selected as control group.A 1∶2 matched case control study was conducted.Complete the questionnaire by consulting the medical records of the hospital and inquiring the parents of the children.The survey items included pregnancy induced hypertension，multifetus，premature rupture of the amniotic fluid，premature birth，low weight at birth，neonatal asphyxia and intracranial hemorrhage(ICH).All data were analyzed with Logistic regression.Results：One way analysis showed that premature birth，low weight at birth，multifetus，pathological jaundice，neonatal asphyxia，premature rupture of the amniotic fluid，hypoxic ischemic encephalopathy and infection were risk factors for cerebral palsy in children(P＜0.05).The multivariate analysis showed that premature birth，low weight at birth，pathological jaundice，neonatal asphyxia and multifetus were main risk factors.Conclusion：The relevant risk factors of CP are various，so taking precautious measures during gestation and perinatal period is important.

Key words: Cerebral palsy, Risk factors, Children