苏前止咳方治疗小儿咳嗽变异性哮喘的疗效观察

doi:10.20274/j.cnki.issn.1674-3865.2025.02.013

Abstract

Abstract: Objective:To observe the clinical effect of Suqian Zike formula in the treatment of pediatric cough variant asthma.Methods:A total of 76 children with cough variant asthma(CVA) (syndrome of pathogenic phelgm accumulating in lungs) but without indications of infection were included as research subjects,who received treatment in the outpatient department of Pediatric Diagnosis and Treatment Center,the Affiliated Hospital of Changchun University of Chinese Medicine from Oct.2022 to Oct.2023,and they were randomly divided into treatment group and control group,38 cases in each group.The control group was given conventional western medicine treatment,and the treatment group was given Suqian Zike formula.The clinical total effective rate,cough symptom score,immune function index level,lung function (FVC,FEV1,FEV1/FVC) and FeNO index level of the two groups were observed.Results:The clinical total effective rate of the treatment group was 94%-74%(36/38),which was significantly higher than 76%-32%(29/38) of thecontrol group(P<0.05).The daytime and night time cough symptom scores and FeNO levels in the treatment group were significantly lower than those in the control group (P<0.05).The levels of IgM,IgG,IgA,FVC,FEV1 and FEV1/FVC in treatment group were significantly higher than those in control group(P<0.05).Conclusion:Suqian Zike formula has remarkable clinical effect in the treatment of pediatric cough variant asthma,and can significantly improve the clinical symptoms and signs of children.

Key words: Cough variant asthma, Syndrome of pathogenic phlegm accumulating in lungs, Suqian Zike formula, Child

TIAN Bing, KONG Yibu, WANG Yongji. Study on the effect of Suqian Zike formula in the treatment of pediatric cough variant asthma[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(2): 159-163.

[1]	Na ZHANG, Dan SUN, Zhengguang HUANG, Shuo YANG. Meta-analysis of the effectiveness of traditional Chinese medicine external therapy for cough variant asthma in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(3): 189-199.
[2]	Zhe ZHOU, Huina LU, Ming ZHANG, Ling DONG. Research on the clinical experience of Professor Xu Rongqian in treating children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 116-121.
[3]	Siang HAN, Xinye ZHANG, Yichen LIN, Chang CAI, Zhenqi WU. On the treatment for pediatric cough variant asthma from the theory of "liver ascending and lung descending" [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(1): 40-44.
[4]	LIANG Chaoqi, LONG Hongyan. Application of San Yin Zhi Yi in the treatment of children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(1): 79-83.
[5]	MING Xi, WANG Ziwei, BIAN Ji, WANG Bo, LU Yingzhu, HUANG Huihui.. Meta-analysis of the efficacy and safety of modified Shegan Mahuang decoction in the treatment of cough variant asthma in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2024, 16(3): 191-197.
[6]	ZHOU Ying, ZHU Haoyu.. Clinical study of traditional Chinese medicine pairs in the treatment of pediatric cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2024, 16(3): 197-200.
[7]	CHE Shuyan, XIE Bin, ZHANG Meng. Study on the pathogenesis of cough variant asthma in children by stages based on the theory of "Xuanfu collaterals" [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2023, 15(3): 250-254.
[8]	SHEN Xiangqing, CHEN Yanxia, GUO Kai. Analysis of pathogenic factors of cough variant asthma in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2022, 14(4): 335-339.
[9]	LI Panpan, WU Liqun, LU Chen, XU Fangwei, CHENG Yuhang. A systematic review of the effectiveness and safety of acupoint application in treating children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(6): 529-536.
[10]	WAN Jun, YU Zhou, SUN Mengtian, YANG Xiangzheng. Clinical observation of modified Xiaoqinglong decoction in the treatment of children with cough variant asthma of external cold and internal fluid type [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(2): 177-.
[11]	LI Panpan, WU Liqun, XU Fangwei, WANG Dongsheng, LU Chen, HONG Jingyu.. Meta-analysis of acupoint application therapy of "summer treatment for winter disease" for children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2020, 12(6): 477-.
[12]	SI Zhenyang. Meta-analysis of pure traditional Chinese medicine in treating cough variant asthma in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(6): 502-506.
[13]	SU Yanqi, WANG Dan, YAN Xinjie, FAN Xue. Diagnostic value of determination of exhaled nitric oxide in children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(3): 200-202.
[14]	ZHANG Xiaolin, WU Huijing, QIU Meixia, ZHAO Tengfei, LIU Kewei. Clinical observation on Yupingfeng powder combined with fluticasone propionate aerosol for cough variant asthma of pulmonosplenic-qi deficiency type in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(2): 159-162.
[15]	WANG Zhihua. Suhuang cough-relieving capsule regulates immunologic function of children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(1): 39-41.

Study on the effect of Suqian Zike formula in the treatment of pediatric cough variant asthma

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments