Abstract: Objective To study the correlation between coagulation indexes and the disease of Mycoplasma pneumoniae lobar pneumonia in children.Methods Totally 99 children with Mycoplasma pneumoniae lobar pneumonia were collected.The following data were recorded:platelet count (PLT),international normalized ratio（INR),plasma prothrombin time(PT),PT activity,activated partial thromboplastin time(APTT),plasma fibrinogen(Fib),thrombin time,plasma D-dimer,syndrome differentiation,fever remission time,cough relief time,rale disappearance time,total duration of disease,length of hospital stay and hospitalization cost.The correlation was analyzed by multiple linear regression statistics.Results There was multiple linear regression relationship between coagulation indexes and length of hospital stay,fever time and hospitalization cost(P<0.05),and the differences were statistically significant.There was a single linear regression relationship between D dimer and disease duration,plasma prothrombin time and cough relief time(P<0.05). Conclusion There is hypercoagulation in the children with lobar pneumonia infected by Mycoplasma pneumoniae.There is a linear regression relationship between the coagulation function and the severity and prognosis of the disease.

Key words:

Lobar pneumonia, Mycoplasma pneumoniae, Coagulation, Relationship, Child