Abstract: Objective  To systematically evaluate the main risk factors for asthma in Chinese children,and provide reference for early prevention and treatment of childhood asthma and improving prognosis.Methods  Retrieve literature researches on risk factors for childhood asthma in China published in China from January 1,2013 to June 11,2023 in CNKI,Wanfang,VIP,and CBM databases.The literature was independently searched and screened,and the data was extracted by two individuals for quality control,Use Excel and NoteExpress software to integrate and verify literature data,and use Stata software for data analysis.Results A total of 24 case-control studies were included for quantitative and qualitative analysis,with a case group of 4 612 cases and a control group of 5 507 cases.The Meta-analysis results showed that allergic rhinitis (OR=5.289,95%CI:2.214-12.631),a history of eczema/dermatitis (OR=4.575,95%CI:1.943-10.774),a family history of asthma (OR=3.708,95%CI:2.662-5.164),respiratory infections (OR=3.483,95%CI:2.362-5.138),and a history of passive smoking (OR=2.407,95%CI:1.984-2.920) were the risk factors for childhood asthma.Conclusion There are many risk factors for asthma attacks in Chinese children,in which allergic rhinitis,history of eczema/dermatitis,family history of asthma,respiratory infections,and a history of passive smoking can increase the risk of asthma in children.

Key words:

Asthma, Risk factors, Meta-analysis, Allergic rhinitis, Child