Abstract:

Objective To explore the relationship between the levels of hormones and vitamin D and obesity in obese preschool children.Methods A total of 128 preschoolers who met the diagnostic criteria for obesity were selected as research subjects. According to the serum vitamin D level, they were divided into appropriate vitamin D group(n=42), insufficient vitamin D group(n=53) and deficient vitamin D group(n=33). The glucolipid metabolism level, vitamin D,Gn, T3, T4 and parathyroid hormone levels of the three groups were compared and analyzed, and the correlation between vitamin D level and the levels of glucolipid metabolism and various hormones levels was analyzed by Person method.Results The levels of FBG, TC, HDL-C, Gn, T3, T4 and parathyroid hormone in vitamin D deficiency group were lower than those in appropriate group and insufficiency group, while the levels of TG and LDL-C were higher(P<0.05). There was a significant correlation between the vitamin D level of deficiency group and insufficiency group and the glucolipid metabolism indexes of children and the levels of T3, T4 and parathyroid hormone (P<0.05), but there was no significant correlation with glucolipid metabolism indexes of children in the appropriate vitamin D group(P>0.05).Conclusion Vitamin D levels in deficiency and insufficiency groups of children are correlated with glucolipid metabolism and hormone levels.

Key words:

Obese, Vitamin D, Clinical mechanism, Preschool children