ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2010, Vol. 2 ›› Issue (1): 49-51.doi: 10.3969/j.issn.1674-3865.2010.01.021

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The preventive effect of anti-asthma particles on inflammatory airway damage of model rats with asthma in remission stage

Xing Xiang hui,Chen Lu,Song Hui Xiao.   

  1. Department of Pediatrics,Shandong University of TCM,Jinan 250011,China.
  • Received:2009-12-30 Published:2010-02-25 Online:2010-02-25

Abstract: Objective:To discuss the mechanism of anti-asthma particles on preventing inflammatory airway damage in asthma remission stage.Methods:Produce rat model of asthma in remission stage to observe the impact of the anti-asthma particles concentrate on the serum IL-4,EOS,and IgE of the model after gastric perfusion.Compare it with Guben Kechuan Tablets and ketotifen positive controlled groups.Results:Anti-asthma particles could reduce levels of serum EOS,inflammatory cytokines IL-4 and immune factors IgE in model rats with asthma in remission stage,and had statistically meaning compared with the positive controlled groups(P<0.05).Conclusions:Anti-asthma particles can inhibit airway inflammation and reduce airway hyper-responsiveness in the model rats,so it has good preventive effect on inflammatory airway damage in model rats with asthma in remission stage.

Key words: Anti-asthma particles/therapeutic, Asthma, IL;EOS, IgE;Rat