ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (2): 121-123.doi: 10.3969/j.issn.1674-3865.2017.02.009

• 临床研究 • 上一篇    下一篇

合生元益生菌冲剂联合复方黄柏液治疗婴幼儿湿疹疗效观察

李方芳   

  1. 471000河南 洛阳，洛阳市中心医院儿科
  • 收稿日期:2016-12-30 出版日期:2017-04-25 上线日期:2017-04-25
  • 通讯作者: 李方芳，E-mail：applefriend3@163.com
  • 作者简介:李方芳(1986-)，女，医学硕士，医师。研究方向：小儿免疫系统疾病的诊治，E-mail：applefriend3@163.com

Biostime probiotics combined with compound Huangbai solution in treatment of childhood eczema: an observation on the efficacy

LI Fangfang   

  1. Department of Pediatrics of Central Hospital of Luoyang，Luoyang 471000，China
  • Received:2016-12-30 Published:2017-04-25 Online:2017-04-25
  • Contact: LI Fangfang，E-mail：applefriend3@163.com

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摘要：
目的：观察口服合生元益生菌冲剂联合外用复方黄柏液在治疗婴幼儿湿疹中的临床疗效。方法：选取2014年8月至2016年1月就诊于洛阳市中心医院儿科门诊的湿疹患儿82例为研究对象，随机分成观察组和对照组各41例。观察组口服合生元益生菌冲剂并配合外用复方黄柏液治疗，对照组只外用复方黄柏液对照治疗，分别观察治疗后2周两组湿疹面积及严重指数(EASI)评分及临床疗效。结果：治疗后1周、治疗后2周观察组、对照组患儿的EASI评分比较，差异有统计学意义(P<0.05)；观察组治疗效果优于对照组，治疗后观察组、对照组总有效率分别是92.1%(35/38)和65.7%(25/38)，差异有统计学意义(P<0.05).结论：在外用复方黄柏液基础上给予口服合生元益生菌冲剂治疗婴幼儿湿疹疗效显著。

关键词: 湿疹, 合生元, 益生菌, 疗效, 肠道菌群, 婴幼儿

Abstract:
Objective：To investigate the clinical efficacy of biostime probiotics combined with compound Huangbai solution in the treatment of eczema in children．Methods：Totally 82 children with eczema treated in our hospital from Aug. 2014 to Jan. 2016 were selected as the subjects, and they were randomly divided into two groups: observation group(A) and control group(B),41 children in each group. Group A was given biostime probiotics combined with external treatment of Huangbai solution，while Group B was only given external treatment of Huangbai solution．The eczema area, EASI scores and the clinical curative effect of two groups were observed after two weeks of treatment．Results：After the treatment of one week and two weeks, the EASI scores were statistically different between the two groups(P<0.05),and the curative effect of Group A was better than that of Group B. The total effective rate in Group A and B was 92.1% and 65.7%, respectively and the difference was statistical(P<0.05)．Conclusion：For children with eczema, the treatment of oral biostime probiotics combined with compound Huangbai solution for external use can achieve significant effect．

Key words: Eczema, Biostime, Probiotics, Curative efficacy, Intestinal flora, Infant